Dr. Zsolt Csenki-Bakos - MATE Research
Overview
Dr. Zsolt Csenki-Bakos specializes in the field of experimental toxicology, primarily working with zebrafish model. His main field of research is the examination of the embryotoxic effects of Endocrine-Disrupting Chemicals (EDCs) and mycotoxins, for which he uses, in addition to the classical protocols, several self-developed alternative test methods and biomarker/bioindicator zebrafish lines. Dr. Csenki-Bakos is at the forefront of leading a research group on aquatic ecotoxicology within the Department of Environmental Toxicology at MATE.
Research keywords:
Publications
method development
Bakos, K., Kovács, R., Balogh, E., Kánainé Sipos, D. I., Reining, M., Gyomorei-Neuberger, O., Balázs, A., Kriszt, B., Bencsik, D., Csepeli, A., Gazsi, G., Hadzhiev, Y., Urbányi, B., Müller, F., Kovács, B., & Csenki, Z. (2019). Estrogen sensitive liver transgenic zebrafish (Danio rerio) line (Tg(vtg1:mCherry)) suitable for the direct detection of estrogenicity in environmental samples. Aquatic Toxicology, 208, 157–167. https://doi.org/10.1016/j.aquatox.2019.01.008
Csenki, Z., Horváth, Á., Bock, I., Garai, E., Kerekes, F., Vásárhelyi, E., Kovács, B., Urbányi, B., Müller, F., & Bakos, K. (2020). Using Tg(Vtg1:mCherry) zebrafish embryos to test the estrogenic effects of endocrine disrupting compounds. Journal of Visualized Experiments, (162), e60462. https://doi.org/10.3791/60462
Kaszab, E., Jiang, D., Szabó, I., Kriszt, B., Urbányi, B., Szoboszlay, S., Sebők, R., Bock, I., & Csenki-Bakos, Z. (2023). Evaluating the in vivo virulence of environmental Pseudomonas aeruginosa using a microinjection model of zebrafish (Danio rerio). Antibiotics, 12(12), 1740. https://doi.org/10.3390/antibiotics12121740
EDC chemicals/biomarker zebrafish development
Csenki, Z., Garai, E., Risa, A., Cserhati, M., Bakos, K., Marton, D., ... & Urbanyi, B. (2019). Biological evaluation of microbial toxin degradation by microinjected zebrafish (Danio rerio) embryos. Chemosphere, 227, 151-161. https://doi.org/10.1016/j.chemosphere.2019.04.014
Csenki, Z., Gubó, E., Garai, E., Bakos, K., Sipos, D. K., Vásárhelyi, E., ... & Plutzer, J. (2022). Microinjection based zebrafish embryo test for the detection of estrogenic substances in slurry based irrigation water and its combined application with yeast estrogen screen. Agricultural Water Management, 272, 107830. https://doi.org/10.1016/j.agwat.2022.107830
Tóth, G., Háhn, J., Szabó, G., Bakos, K., Volner, C., Liang, X., ... & Csenki, Z. (2024). In vivo estrogenicity of glyphosate, its formulations, and AMPA on transgenic zebrafish (Danio rerio) embryos. Environmental Pollution, 342, 123113. https://doi.org/10.1016/j.envpol.2023.123113
mycotoxin research
Csenki, Z., Garai, E., Faisal, Z., Csepregi, R., Garai, K., Sipos, D. K., ... & Poór, M. (2021). The individual and combined effects of ochratoxin A with citrinin and their metabolites (ochratoxin B, ochratoxin C, and dihydrocitrinone) on 2D/3D cell cultures, and zebrafish embryo models. Food and Chemical Toxicology, 158, 112674. https://doi.org/10.1016/j.fct.2021.112674
Csenki, Z., Risa, A., Sárkány, D., Garai, E., Bata-Vidács, I., Baka, E., Szekeres, A., Varga, M., Ács, A., Griffitts, J., Bakos, K., Bock, I., Szabó, I., Kriszt, B., Urbányi, B., & Kukolya, J. (2022). Comparison Evaluation of the Biological Effects of Sterigmatocystin and Aflatoxin B1 Utilizing SOS-Chromotest and a Novel Zebrafish (Danio rerio) Embryo Microinjection Method. Toxins, 14(4), 252. https://doi.org/10.3390/toxins14040252
Csenki, Z., Bock, I., Horváth, L., Stepniak, A., Fiser, B., Buczkowski, A., ... & Poór, M. (2025). Toxic effects of palmitoyl-, oleoyl-, and linoleoyl-fumonisin B1 derivatives on zebrafish embryos and their interactions with serum albumin. Emerging Contaminants, 100620. https://doi.org/10.1016/j.emcon.2025.100620
Projects
REPurpose - "Repurposing post-consumer waste into recyclable rubbery plastics" funded by the European Union (Grant Agreement No 101057971)
REPurpose aims to develop a Safe-and-Sustainable-by-Design platform where local post-consumer waste is upcycled into new functional REP polymers for the thermoplastic elastomers high-value market. https://www.repurposeproject.eu/
WaterGreenTreat „A green approach in the frame of circular economy: robocasted photocatalysts for wastewater treatment and use of reclaimed water in agriculture.” (Water4All-2022-FP-00049)
The project aims to obtain photocatalysts based on ecogenic metal oxide composites for the removal of pharmaceutically active compounds and dyes in wastewater treatment and thus facilitate the use of regenerated water in agriculture.
BioTreatED- Advanced Bio-Based Solutions to Monitor and Mitigate Hormonal Risks from Irrigation Waters Derived from Manure Separation Technologies
The project offers a new concept to mitigate the risks of steroid hormones and hormonally active compounds found in the solid and liquid fractions separated from livestock slurry. The project aims to develop a hormone-degrading microbial consortium and a comprehensive monitoring methodology to protect agricultural and aquatic ecosystems.
https://water4all-biotreated.uni-mate.hu/en/home
